MetalloBio.
MetalloBio is a deep-tech pharmaceutical company that has developed a novel antimicrobial chemistry platform to address the growing threat posed by untreatable infections (or antimicrobial resistance - AMR). They focus on advancing lead compounds that represent a groundbreaking new class of antibiotics towards the clinic.
- Client
- MetalloBio
- Who they are
- Co-founded by Dr Kirsty Smitten and Professor Jim Thomas from the University of Sheffield’s Department of Chemistry, MetalloBio was established in 2021 as a spin-out company focused on the development of new antimicrobial technologies.
- What they do
- MetalloBio is developing a novel chemistry platform that provides for the design, synthesis and rapid scale-up manufacture of antimicrobially active chemical compounds. Their focus is currently on two lead candidates; KLS116 is advancing through the stages of pre-clinical drug development towards expected phase 1 clinical trials in 2026, whereas KLS 219 is being developed for materials-based applications such as medical device and apparatus coatings. In either case, the technology is designed to be active against the most pernicious of drug-resistant bacteria.
- Location
- Sheffield
- Requirements
- Conduct a brand refresh and redesign of their existing website by facilitating workshops.
problem
MetalloBio’s existing Squarespace website had limited functionality, making it difficult for them to showcase their work effectively. They noticed that the current state of their website didn’t truly reflect the current status of their organisation and wanted a website and branding refresh.result
We collaborated with MetalloBio to deliver a redesigned and developed website using WebFlow. We chose this specific Content Management System (CMS) due to its functionality and flexibility, and this solution worked perfectly with their budget and business needs. Alongside changing their CMS, we also refreshed their branding to provide a more subtle and balanced set of visual assets that better represent their vision, mission and brand identity.We worked with the Hive IT team for several weeks on this project, even before the creative work started. For us, the company website is many different things: an absolutely core part of our web presence; our front of house (for many, our website is their first encounter with MetalloBio); a conduit for MetalloBio news flow and updates; a shop window for investors and potential commercial partners, and, in time, an educational resource aligned with our mission to improve the prospects for patients with untreatable infections. It is no accident that the website Hive IT built delivers these attributes. They comprehensively drilled down into every detail and nuance of what we were seeking to achieve. This takes time and focus. They ran the information-gathering sessions superbly. At times, it was not abundantly apparent where all the strands of questioning were going: the questions in isolation made sense, but how could they possibly lead to a cogent and neatly structured website that would meet our expectations and needs? This is part of the Hive IT magic. They were able to draw it all together. It suddenly made complete sense. The result, we believe is truly excellent. But it took our full commitment to the process, and our willingness to surrender to the Hive IT approach. It was worth it. Really, very well worth it.Dr Richard Senior, CHIEF OPERATING OFFICER
Branding and Design
Our first step was understanding how to build MetalloBio’s new redesigned website and foundations as an organisation. We started with an Impact Mapping session, a collaborative exercise that distilled the company’s goals and challenges into clear actionable insights for the website. This allowed us to answer critical questions:
- What drives their mission?
- Who are the key stakeholders in achieving this mission?
- What behaviours or actions do we need to encourage?
- What barriers might stand in their way?
- How can we overcome these challenges?
This map didn’t just outline a strategy, it offered a lens through which we could prioritise content, identify user needs, and design a website structure that made sense. From here, we created a sitemap to visualise the flow of content, balancing accessibility with engagement. This structured foundation allowed us to design efficiently, ensuring every page had purpose and clarity.
Discovering MetalloBio’s brand ambition and identity
Through branding workshops, we dove deeper into MetalloBio’s identity. These sessions weren’t just about aesthetics; they were about uncovering the heart of the organisation - what drives them, how they want to be seen, and the impact they hope to achieve.
Through the use of different branding activities, we encouraged divergent thinking to uncover fresh perspectives. These exercises helped define MetalloBio’s ambition as a company that combines groundbreaking innovation with approachable expertise, challenging the norms of the pharmaceutical industry.
From these insights, we developed a brand foundation document - a guide that distilled their mission (“Driving out life-threatening infections with radical antibiotic solutions”), values (resilience, collaboration, excellence), and tone of voice (confident yet approachable, thoughtful yet purposeful). This document became a cornerstone for all design and communication efforts.
The visual identity
The aim of the branding work was never to start again from scratch, but instead the focus was building on top of and being sympathetic to the current logo, styles and colours to respect and pay tribute to the legacy of Dr Kirsty Smitten (MetalloBio’s co-founder), who sadly died from serial lung infections following treatment for the rare and aggressive cancer, cardiac angiosarcoma.
Building on their established aesthetic, we updated their visual assets to reflect their modern, confident, and innovative personality.
Deliverables included:
A refreshed logo - Adjustments ensured greater versatility across digital and print.
Updated fonts and colour palette - These elements balanced professionalism with a modern edge, emphasising clarity and approachability.
Business and presentation materials - From slide templates to letterheads and business cards, each piece was designed to reflect MetalloBio’s credibility and innovation.
These assets were packaged and organised for convenient use, ensuring that any future collaborators can maintain their visual identity and language consistently while allowing flexibility.
We ensured that the site wasn’t just visually compelling but also a platform to amplify their mission. The design needed to embody their “groundbreaking yet grounded” approach, using clean lines, calming colours, and bold accents to convey not only confidence but urgency.
Website Redesign
We worked closely with MetalloBio to develop an effective and engaging website architecture. This was done by working with them to develop a content structure that informed the new website design. Each layout highlights MetalloBio’s three pillars of innovation, awareness, and advocacy while ensuring easy navigation for diverse audiences.
The website features and improvements had to appeal to their target audiences which were investors, partners as well as the general public with an interest in antimicrobial resistance (AMR).
Our Head of Creative, Allan, gathered all the relevant information to create fresh design templates that are modern, user-friendly and that better communicate MetalloBio’s work.
We helped transition MetalloBio from their old SquareSpace Content Management System (CMS), which restricted them by having limited features and functionality to WebFlow. WebFlow has a combined design tool and CMS which reduces the time we can design and develop a site, whilst still producing a high-quality product that is responsive and accessible.
By choosing this CMS for MetalloBio they will gain various benefits and free them from previous limitations. For example,
- A user-friendly experience that simplifies the design process.
- Freedom to create a website without being tied to a template, allowing them to differentiate themselves from competitors.
- The capability to concept and build all within one system, enabling rapid development and adaptability to change.
- An integrated responsive design feature which ensures minimal development work, means the new site will be responsive across the latest mobile and tablet devices.
Technology
Webflow: Designing a CMS-Driven Website
Webflow allowed us a quick and easy way to transform design concepts into a fully functional and content-managed website. It includes:
- Dynamic CMS - Giving MetalloBio the ability to manage blog posts, case studies, and other content independently, reducing reliance on developer or designer input.
- Responsive Design - A quick way to ensure that the site works across devices, providing a consistent experience for users.
Miro: Facilitation Workshops and Ideation
Miro was the backbone of our discovery and collaboration workshops. This tool helped us:
- Brainstorm Ideas - Using digital whiteboards, we developed ideas and mapped out concepts such as impact maps and audience personas.
- Enhance Engagement - Helped with interactive exercises like card sorting and branding analogies, which allowed us to keep sessions dynamic and inclusive.
- Maintain Alignment - All workshop insights were captured in one place, making it easy to reference and build upon as the project progressed.
Adobe Illustrator: refining the brand identity
Adobe Illustrator was essential for crafting and fine-tuning MetalloBio’s visual assets. We:
- Refreshed the Logo - Made adjustments to ensure scalability and readability across digital and print mediums
- Enhanced Visual Elements - created high-quality graphics and icons that aligned with the updated brand foundation
Developed Templates - Designed professional slide decks, letterheads, and business cards to ensure MetalloBio’s branding remained consistent across all channels.
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